IsoSeal-Plus Positive Pressure (Recirculating) Compounding Aseptic Isolators



  • superior egonomic design & styling
  • all stainless steel work zone construction with radiused & crevice-free corners
  • spacious work zone interior
  • smooth opening / closing pneumatically controlled viewing window
  • large diameter glove ports ergonomically located for greater operator arms movement
  • independent sterile entry & exit transfer chambers with HEPA filtration
  • sliding chamber trays for easy access & transfer of product
  • microprocessor-controlled diagnostic system with digital display & audible alarm
  • hourmeter
  • delayed-automatic-off timer
  • elapsed / event timer
  • ISO Class 5 (Class 100) air cleanliness work zone for absolute product protection
  • reliability-proven design & performance


Gelman IsoSeal-Plus Positive Pressure (Recirculating) Compounding Aseptic Isolators are effective laboratory aids in obtaining the optimum control over product quality and meet the needs of pharmacy applications involving compounding and dispensing of non-hazardous pharmaceuticals or drugs, preparation of IV solutions and eyedrops, TPN (Total Parenteral Nutrition), ampoule filling, quality controls and pharmacy routines that require absolute sterility.
The IsoSeal-Plus Positive Pressure (Recirculating) Isolators are commonly used for sterility testing of pharmaceutical products before release to market for distribution and use.


The IsoSeal-Plus Positive Pressure (Recirculating) Compounding Aseptic Isolator offers a contained, positive pressure work zone to provide aseptic conditions within the work area for product protection.
Unidirectional HEPA-filtered airflow within the work zone minimizes cross-contamination across the work area.
An effective physical barrier between the work zone and the environment is maintained by air-tight viewing windows.
The isolator work zone are maintained at a positive pressure to the room with the work area pressure slightly more positive than the independent entry & exit transfer chambers.
Operations in the isolator are carried out through rubber gloves attached to large diameter glove ports, ergonomically located for greater operator arms movement.
The main viewing window with the glove ports attached, is hinged along the top and may be fully opened for cleaning, loading and unloading of auxiliary equipment.
The independent entry & exit transfer chambers are equipped with external doors to the outside and an inter-chamber vertical sliding doors to the work area. The inter-chamber
doors allow operator to introduce or remove items from the work area while maintaining the internal aseptic conditions.


Microprocessor-controlled diagnostic system with digital display & audible alarm



*Total width after assembly of transfer chambers

Gelman IsoSeal-Plus Series Positive Pressure (Recirculating) Compounding Aseptic Isolators are manufactured under a rigorous Total Quality Management in full compliance with ISO 9001:2015, CETA CAG-001-2005, CETA CAG-002-2006 and
USP 797 / USP 800.