IsoGuard ISO Series Type 2 Negative Pressure (Total Exhaust) Pharmaceutical Isolators With Primary Containment HEPA Filtration System



  • unique primary containment HEPA filtration system for maximum personnel,product & environment protection
  • superior ergonomic design & styling
  • negative pressure double-wall housings for containment
  • all stainless steel work zone construction with radiused & crevice-free corners
  • spacious work zone interior
  • smooth opening/closing pneumatically controlled viewing window
  • large diameter glove ports ergonomically located for greater operator arms movement
  • independent sterile entry & exit transfer chambers with HEPA filtration
  • sliding chamber trays for easy access & transfer of product
  • microprocessor-controlled diagnostic system with digital display & audible alarm
  • delayed-automatic-off timer
  • hourmeter
  • elapsed timer
  • ISO Class 5 (Class 100) air cleanliness work zone for absolute product protection
  • reliability-proven design & performance


Gelman IsoGuard ISO Series Type 2 Negative Pressure (Total Exhaust) Pharmaceutical Isolators are designed for compounding of highly volatile hazardous drugs or potent pharmaceutical compounds, chemotherapy agents and IV mixtures that can be harmful to pharmacy personnel and require both containment and aseptic manipulation.
Gelman IsoGuard ISO Series Type 2 Negative Pressure (Total Exhaust) Pharmaceutical Isolator is an effective laboratory aid in providing total protection for

  • all personnel and environment from any aerosol, particles or vapours which may be liberated in the preparation, manipulation and dispensing of volatile hazardous drugs.
  • drug products so that they are prepared or dispensed in an environment free from particulates including biological matter.
  • maintenance and testing personnel from exposure to the residue of drug products which may contaminate cabinet filters, mechanical components and other surfaces.


Gelman IsoGuard ISO Series Type 2 Negative Pressure (Total Exhaust) Pharmaceutical Isolator offers a contained, negative pressure work zone to prevent migration of hazardous contaminants to the environment.
Unidirectional HEPA-filtered airflow within the work zone and transfer chambers minimizes cross-contamination across the work area.
An effective physical barrier between the operator and the work zone, maintained by an air-tight viewing window provides personnel protection.
The work zone is maintained at a negative pressure to the room with the transfer chambers pressure slightly more negative than the work area.
Operations in the isolator are carried out through rubber gloves attached to large diameter glove ports, ergonomically located for greater operator arms movement.
The main viewing window with the glove ports attached, is hinged along the top and may be fully opened for cleaning, loading and unloading of auxiliary equipment.
The transfer chambers are equipped with external doors to the outside and inter-chamber doors to the work zone. The inter-chamber doors allow operators to introduce or remove items from the work zone while maintaining the internal aseptic conditions.

Ambient air is drawn in through an  intake prefilter on top of the isolator and is introduced to the work area through a supply HEPA filter.
HEPA-filtered vertical airflow free from airborne contaminants is projected downwards over the work surface to create an ultra-clean air cleanliness work area for aseptic work and product protection.
Independent C2 Type HEPA-filtered entry & exit transfer chambers with prefilters, fitted to the sides of the isolator provide sterile entry/exit of product from the work area.
The air from the transfer chambers blend with the contaminated work area air in a sump beneath the work surface and is filtered by a primary containment HEPA filter located below the work zone. The filter arrests all particulates released within the work zone, thereby protecting fan, other internal components, maintenance technicians and the environment from contamination.
The filtered air is totally discharged to the outside atmosphere via a dedicated facility exhaust system after being treated by a final exhaust HEPA filter, without recirculation in the cabinet or return to the laboratory.
An exhaust Terminal Fan Module can be installed when the building exhaust system is inadequate to overcome the static pressure of the cabinet.


Microprocessor-controlled diagnostic system with digital display & audible alarm



*Total width after assembly of transfer chambers

Gelman IsoGuard ISO Series Pharmaceutical Type 2 Negative Pressure (Recirculating) Isolators with Primary Containment HEPA Filtration System are manufactured under a rigorous Total Quality Management in full compliance with ISO 9001:2015, CETA CAG-001-2005, CETA CAG-002-2006 and
USP 797 / USP 800.